CMap Candidate Details

Structure:
CMap ID: C20686
Pert ID: BRD-K57371763
Compound Name: fidaxomicin
Targets: --
MoA: --
SMILES: CC[C@H]1C=C(C)/[C@@H](O)CC=CC=C(CO[C@@H]2O[C@H](C)[C@@H](OC(=O)c3c(O)c(Cl)c(O)c(Cl)c3CC)[C@H](O)[C@@H]2OC)C(=O)O[C@H](CC=C(C)C=C(C)[C@H]1O[C@@H]1OC(C)(C)[C@@H](OC(=O)C(C)C)[C@H](O)[C@H]1O)[C@@H](C)O
InchiKey: ZVGNESXIJDCBKN-MHDOWYNASA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
123515 BRD-K57371763 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123534 BRD-K57371763 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.37 -1.23 1.25
123562 BRD-K57371763 HEK293 0.125 uM 24 h 0.27 1.14 0.3 0.22 0.79 0.07
123613 BRD-K57371763 HELA 10 uM 24 h 0.0 0.0 0.0 -0.36 -1.23 1.25
123640 BRD-K57371763 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123679 BRD-K57371763 MCF10A 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123722 BRD-K57371763 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123741 BRD-K57371763 PC3 10 uM 24 h 0.0 0.0 0.0 -0.38 -1.27 1.39
132133 BRD-K57371763 YAPC 2.22 uM 24 h 0.0 0.0 0.0 -0.42 -1.4 2.02
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).