CMap Candidate Details
Structure:
CMap ID: | C20691 |
Pert ID: | BRD-K57391913 |
Compound Name: | iloprost |
Targets: | PTGER1; PTGER2; PTGIR |
MoA: | Prostanoid receptor agonist; Platelet aggregation inhibitor |
SMILES: | CC(C)N(CCCCOCC(O)=O)c1cnc(-c2ccccc2)c(n1)-c1ccccc1 |
InchiKey: | OJQMKCBWYCWFPU-UHFFFAOYSA-N |
Compound Aliases: | -- |
Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
---|---|---|---|---|---|---|---|---|---|---|
1011 | BRD-K57391913 | CD34 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | -0.43 | -1.44 | 15.35 |
1023 | BRD-K57391913 | HL60 | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
1081 | BRD-K57391913 | PC3 | 0.37 uM | 6 h | 0.0 | 0.0 | 0.0 | -0.32 | -1.09 | 0.83 |
1097 | BRD-K57391913 | U937 | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |