CMap Candidate Details

Structure:
CMap ID: C20699
Pert ID: BRD-K57432881
Compound Name: tiapride
Targets: DRD2; DRD3
MoA: Dopamine receptor antagonist
SMILES: CCN(CC)CCNC(=O)c1cc(ccc1OC)S(C)(=O)=O
InchiKey: JTVPZMFULRWINT-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
99693 BRD-K57432881 U2OS 10 uM 6 h 0.25 1.03 0.13 0.0 0.0 0.0
123795 BRD-K57432881 A375 1.11 uM 24 h 0.0 0.0 0.0 0.19 0.68 0.01
123837 BRD-K57432881 A549 0.37 uM 24 h 0.0 0.0 0.0 -0.2 -0.67 0.02
123870 BRD-K57432881 HA1E 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123898 BRD-K57432881 HEK293 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123943 BRD-K57432881 HELA 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123964 BRD-K57432881 HT29 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123999 BRD-K57432881 JURKAT 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124052 BRD-K57432881 MCF10A 0.04 uM 24 h 0.0 0.0 0.0 -0.24 -0.82 0.15
124122 BRD-K57432881 MDAMB231 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124181 BRD-K57432881 THP1 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124233 BRD-K57432881 YAPC 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132252 BRD-K57432881 MCF??7.00 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132296 BRD-K57432881 PC3 0.08 uM 24 h 0.0 0.0 0.0 -0.39 -1.31 1.71
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).