CMap Candidate Details

Structure:
CMap ID: C20844
Pert ID: BRD-K58033748
Compound Name: BRD-K58033748
Targets: CHRM1
MoA: Acetylcholine receptor antagonist
SMILES: O=C(CCNS(=O)(=O)c1cccc2nsnc12)N1CCN(CC1)c1ccncc1
InchiKey: WXDHQWPQLKGANZ-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
16513 BRD-K58033748 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
16717 BRD-K58033748 A549 10 uM 6 h 0.0 0.0 0.0 0.29 1.04 0.55
17046 BRD-K58033748 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
17383 BRD-K58033748 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
17722 BRD-K58033748 HT29 10 uM 6 h 0.0 0.0 0.0 -0.28 -0.96 0.42
18004 BRD-K58033748 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.35 1.25 1.29
18307 BRD-K58033748 PC3 10 uM 24 h 0.0 0.0 0.0 0.22 0.79 0.08
18799 BRD-K58033748 VCAP 10 uM 6 h 0.0 0.0 0.0 0.29 1.03 0.51
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).