CMap Candidate Details

Structure:
CMap ID: C02086
Pert ID: BRD-A85025557
Compound Name: NCS-382
Targets: GABBR1; SLC52A2; GABBR2
MoA: GABA receptor antagonist
SMILES: OC1c2ccccc2CCCC1=C/C(O)=O
InchiKey: UADPGHINQMWEAG-CSKARUKUSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5416 BRD-A85025557 HA1E 10 uM 6 h 0.22 0.91 0.03 -0.26 -0.86 0.22
5555 BRD-A85025557 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
6495 BRD-A85025557 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44496 BRD-A85025557 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44791 BRD-A85025557 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
45112 BRD-A85025557 HEPG2 10 uM 6 h 0.33 1.37 0.97 0.22 0.78 0.06
45383 BRD-A85025557 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45753 BRD-A85025557 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45911 BRD-A85025557 NPC 10 uM 24 h 0.19 0.79 0.0 0.0 0.0 0.0
46228 BRD-A85025557 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46543 BRD-A85025557 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
97134 BRD-A85025557 A375 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
97202 BRD-A85025557 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).