CMap Candidate Details

Structure:
CMap ID: C20892
Pert ID: BRD-K58211978
Compound Name: roxithromycin
Targets: --
MoA: --
SMILES: CC[C@H]1OC(=O)[C@H](C)[C@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@@H]([C@H]2O)N(C)C)[C@](C)(O)C[C@@H](C)C(=N/OCOCCOC)[C@H](C)[C@@H](O)[C@]1(C)O
InchiKey: RXZBMPWDPOLZGW-IVJCFNEOSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
123535 BRD-K58211978 HA1E 3.33 uM 24 h 0.0 0.0 0.0 -0.27 -0.89 0.27
123564 BRD-K58211978 HEK293 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123681 BRD-K58211978 MCF10A 0.04 uM 24 h 0.0 0.0 0.0 -0.25 -0.84 0.17
131974 BRD-K58211978 A375 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132031 BRD-K58211978 HELA 0.08 uM 24 h -0.24 -1.01 0.17 0.32 1.13 0.85
132057 BRD-K58211978 HT29 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132074 BRD-K58211978 MCF??7.00 2.22 uM 24 h -0.21 -0.88 0.03 -0.26 -0.86 0.22
132105 BRD-K58211978 PC3 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132135 BRD-K58211978 YAPC 0.01 uM 24 h 0.0 0.0 0.0 0.26 0.93 0.27
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).