CMap Candidate Details

Structure:
CMap ID: C02093
Pert ID: BRD-A85424553
Compound Name: thioperamide
Targets: HRH3; HRH4
MoA: Histamine receptor antagonist
SMILES: S=C(NC1CCCCC1)N2CCC(CC2)C3C=NC=N3
InchiKey: JFAYRTHYLOZRNL-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
2976 BRD-A85424553 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
3326 BRD-A85424553 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
3591 BRD-A85424553 PC3 10 uM 6 h 0.0 0.0 0.0 -0.22 -0.74 0.05
3706 BRD-A85424553 VCAP 10 uM 24 h 0.0 0.0 0.0 -0.31 -1.04 0.66
44653 BRD-A85424553 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44792 BRD-A85424553 ASC 10 uM 24 h 0.26 1.09 0.22 0.0 0.0 0.0
45113 BRD-A85424553 HEPG2 10 uM 6 h -0.27 -1.13 0.4 0.0 0.0 0.0
45384 BRD-A85424553 HT29 10 uM 6 h -0.23 -0.97 0.1 0.27 0.97 0.35
45754 BRD-A85424553 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45912 BRD-A85424553 NPC 10 uM 24 h 0.0 0.0 0.0 -0.42 -1.43 15.35
46229 BRD-A85424553 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46544 BRD-A85424553 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).