CMap Candidate Details

Structure:
CMap ID: C02097
Pert ID: BRD-A85587465
Compound Name: bemesetron
Targets: HTR3A
MoA: Serotonin receptor antagonist
SMILES: CN1C2CCC1CC(C2)OC(=O)c1cc(Cl)cc(Cl)c1
InchiKey: MNJNPLVXBISNSX-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
2823 BRD-A85587465 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3123 BRD-A85587465 HCC515 10 uM 24 h 0.22 0.92 0.04 0.0 0.0 0.0
3707 BRD-A85587465 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39288 BRD-A85587465 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39603 BRD-A85587465 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39923 BRD-A85587465 HEPG2 10 uM 6 h 0.23 0.94 0.06 0.0 0.0 0.0
40208 BRD-A85587465 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40441 BRD-A85587465 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
40726 BRD-A85587465 NEU 10 uM 24 h 0.0 0.0 0.0 -0.34 -1.14 1.01
41028 BRD-A85587465 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41351 BRD-A85587465 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
96324 BRD-A85587465 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
96394 BRD-A85587465 PC3 10 uM 24 h 0.0 0.0 0.0 0.29 1.04 0.55
100368 BRD-A85587465 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
136406 BRD-A85587465 SHSY5Y 0.04 uM 24 h 0.0 0.0 0.0 -0.39 -1.32 1.71
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).