CMap Candidate Details
Structure:
| CMap ID: | C20973 |
| Pert ID: | BRD-K58486055 |
| Compound Name: | reparixin |
| Targets: | CXCR1; CXCR2 |
| MoA: | CCK receptor antagonist |
| SMILES: | CC(C)Cc1ccc(cc1)[C@@H](C)C(=O)NS(C)(=O)=O |
| InchiKey: | KQDRVXQXKZXMHP-LLVKDONJSA-N |
| Compound Aliases: | -- |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 123565 | BRD-K58486055 | HEK293 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 123615 | BRD-K58486055 | HELA | 0.04 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 123682 | BRD-K58486055 | MCF10A | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 131975 | BRD-K58486055 | A375 | 0.74 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 132007 | BRD-K58486055 | HA1E | 0.03 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.41 | -1.39 | 2.02 |
| 132058 | BRD-K58486055 | HT29 | 0.03 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 132075 | BRD-K58486055 | MCF??7.00 | 0.01 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 132106 | BRD-K58486055 | PC3 | 0.25 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.18 | -0.62 | 0.0 |
| 132136 | BRD-K58486055 | YAPC | 0.01 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.19 | -0.64 | 0.01 |