CMap Candidate Details

Structure:
CMap ID: C20981
Pert ID: BRD-K58501140
Compound Name: TAK-875
Targets: FFAR1
MoA: Insulin secretagogue
SMILES: Cc1cc(OCCCS(C)(=O)=O)cc(C)c1-c1cccc(COc2ccc3[C@H](CC(O)=O)COc3c2)c1
InchiKey: BZCALJIHZVNMGJ-HSZRJFAPSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
123516 BRD-K58501140 A375 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123566 BRD-K58501140 HEK293 10 uM 24 h 0.25 1.02 0.13 -0.35 -1.18 1.14
123616 BRD-K58501140 HELA 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123642 BRD-K58501140 HT29 0.37 uM 24 h 0.0 0.0 0.0 -0.4 -1.35 2.02
123683 BRD-K58501140 MCF10A 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123723 BRD-K58501140 MCF??7.00 0.125 uM 24 h 0.0 0.0 0.0 -0.28 -0.94 0.39
123742 BRD-K58501140 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123761 BRD-K58501140 YAPC 10 uM 24 h 0.0 0.0 0.0 -0.26 -0.89 0.26
132008 BRD-K58501140 HA1E 0.08 uM 24 h 0.0 0.0 0.0 -0.26 -0.89 0.26
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).