CMap Candidate Details

Structure:
CMap ID: C02099
Pert ID: BRD-A85667082
Compound Name: fulvestrant
Targets: ESR1
MoA: Estrogen receptor antagonist
SMILES: C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2O)[C@H](CCCCCCCCCS(=O)CCCC(F)(F)C(F)(F)F)Cc1cc(O)ccc31
InchiKey: VWUXBMIQPBEWFH-WCCTWKNTSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
91460 BRD-A85667082 HUH7 6.66 uM 72 h 0.0 0.0 0.0 0.0 0.0 0.0
104249 BRD-A85667082 U2OS 20 uM 6 h 0.0 0.0 0.0 0.25 0.89 0.2
116292 BRD-A85667082 A375 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
116334 BRD-A85667082 A549 10 uM 24 h -0.32 -1.33 0.9 0.0 0.0 0.0
116375 BRD-A85667082 HA1E 3.33 uM 24 h 0.0 0.0 0.0 -0.29 -0.97 0.46
116422 BRD-A85667082 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
116474 BRD-A85667082 HEPG2 3.33 uM 24 h 0.0 0.0 0.0 -0.35 -1.19 1.16
116524 BRD-A85667082 HT29 10 uM 24 h 0.17 0.69 0.0 0.0 0.0 0.0
116571 BRD-A85667082 MCF??7.00 0.125 uM 24 h -0.24 -1.01 0.16 -0.39 -1.32 1.71
116610 BRD-A85667082 PC3 10 uM 24 h 0.29 1.21 0.47 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).