CMap Candidate Details

Structure:
CMap ID: C02103
Pert ID: BRD-A85860691
Compound Name: chaetocin
Targets: SUV39H1
MoA: Histone lysine methyltransferase inhibitor
SMILES: CN1C(=O)C23CC4(C(Nc5ccccc54)N3C(=O)C1(CO)SS2)C67CC8(SSC9(CO)N(C)C8=O)N(C7Nc%10ccccc%106)C9=O
InchiKey: PZPPOCZWRGNKIR-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
9056 BRD-A85860691 A375 0.08 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9319 BRD-A85860691 AGS 0.08 uM 6 h -0.17 -0.73 0.0 0.0 0.0 0.0
9622 BRD-A85860691 H1299 0.08 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9974 BRD-A85860691 HA1E 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
10342 BRD-A85860691 HCC515 0.08 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10425 BRD-A85860691 HCT116 0.08 uM 6 h 0.0 0.0 0.0 0.25 0.89 0.21
10697 BRD-A85860691 HEPG2 0.08 uM 6 h 0.0 0.0 0.0 -0.18 -0.62 0.0
11108 BRD-A85860691 HT29 0.08 uM 6 h -0.28 -1.18 0.51 0.0 0.0 0.0
11255 BRD-A85860691 MCF??7.00 0.08 uM 6 h -0.23 -0.95 0.09 0.0 0.0 0.0
11374 BRD-A85860691 NCIH2073 0.08 uM 6 h -0.25 -1.06 0.25 0.0 0.0 0.0
11944 BRD-A85860691 NCIH596 0.08 uM 6 h 0.0 0.0 0.0 -0.27 -0.92 0.33
12228 BRD-A85860691 NOMO1 0.08 uM 6 h -0.22 -0.93 0.07 0.34 1.19 1.02
12584 BRD-A85860691 PC3 0.08 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12693 BRD-A85860691 SW480 0.08 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13172 BRD-A85860691 U937 0.08 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13556 BRD-A85860691 VCAP 0.08 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
90539 BRD-A85860691 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
96069 BRD-A85860691 PHH 3.33 uM 24 h 0.0 0.0 0.0 0.36 1.27 1.32
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).