CMap Candidate Details

Structure:
CMap ID: C02109
Pert ID: BRD-A86248581
Compound Name: tetrahydrouridine
Targets: CDA
MoA: Cytidine deaminase inhibitor
SMILES: OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1CCC(O)NC1=O
InchiKey: UCKYOOZPSJFJIZ-XVKVHKPRSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
126021 BRD-A86248581 HA1E 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126064 BRD-A86248581 HT29 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126103 BRD-A86248581 HUVEC 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126157 BRD-A86248581 JURKAT 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126208 BRD-A86248581 MCF10A 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126249 BRD-A86248581 MDAMB231 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126327 BRD-A86248581 THP1 1.11 uM 24 h -0.2 -0.84 0.01 0.0 0.0 0.0
134025 BRD-A86248581 A375 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134056 BRD-A86248581 A549 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134131 BRD-A86248581 HEK293 0.74 uM 24 h 0.19 0.8 0.0 0.29 1.02 0.48
134169 BRD-A86248581 HELA 0.25 uM 24 h 0.0 0.0 0.0 0.35 1.23 1.24
134246 BRD-A86248581 MCF??7.00 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134299 BRD-A86248581 PC3 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134333 BRD-A86248581 YAPC 0.74 uM 24 h 0.0 0.0 0.0 0.33 1.18 0.98
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).