CMap Candidate Details

Structure:
CMap ID: C02117
Pert ID: BRD-A86871940
Compound Name: nicaraven
Targets: --
MoA: --
SMILES: CC(CNC(=O)c1cccnc1)NC(=O)c1cccnc1
InchiKey: KTXBOOWDLPUROC-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
125973 BRD-A86871940 A375 0.125 uM 24 h -0.2 -0.83 0.0 0.28 0.99 0.39
126040 BRD-A86871940 HELA 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126156 BRD-A86871940 JURKAT 0.04 uM 24 h 0.33 1.37 0.97 0.0 0.0 0.0
126207 BRD-A86871940 MCF10A 0.04 uM 24 h 0.22 0.92 0.04 0.3 1.05 0.57
126277 BRD-A86871940 PC3 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126326 BRD-A86871940 THP1 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134055 BRD-A86871940 A549 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134078 BRD-A86871940 HA1E 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134130 BRD-A86871940 HEK293 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134198 BRD-A86871940 HT29 2.22 uM 24 h 0.21 0.9 0.02 0.0 0.0 0.0
134215 BRD-A86871940 HUVEC 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134245 BRD-A86871940 MCF??7.00 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134277 BRD-A86871940 MDAMB231 0.03 uM 24 h 0.0 0.0 0.0 -0.32 -1.09 0.82
134332 BRD-A86871940 YAPC 0.01 uM 24 h -0.22 -0.91 0.05 0.19 0.69 0.01
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).