CMap Candidate Details

Structure:
CMap ID: C21190
Pert ID: BRD-K59163477
Compound Name: cisapride
Targets: HTR4; KCNH2
MoA: Serotonin receptor agonist
SMILES: CO[C@@H]1CN(CCCOc2ccc(F)cc2)CC[C@@H]1NC(=O)c3cc(Cl)c(N)cc3OC
InchiKey: DCSUBABJRXZOMT-RBBKRZOGSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
6897 BRD-K59163477 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
7185 BRD-K59163477 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
7347 BRD-K59163477 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
7697 BRD-K59163477 HCC515 10 uM 6 h 0.0 0.0 0.0 -0.28 -0.95 0.4
8018 BRD-K59163477 HT29 10 uM 6 h 0.0 0.0 0.0 0.2 0.72 0.02
8109 BRD-K59163477 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
8525 BRD-K59163477 PC3 10 uM 6 h -0.2 -0.84 0.0 0.0 0.0 0.0
8712 BRD-K59163477 VCAP 10 uM 24 h 0.24 0.99 0.1 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).