CMap Candidate Details

Structure:
CMap ID: C02120
Pert ID: BRD-A87125127
Compound Name: 3-matida
Targets: GRM1
MoA: Glutamate receptor antagonist
SMILES: Cc1cc(sc1C(N)C(=O)O)C(=O)O
InchiKey: KOMWRBFEDDEWEP-UHFFFAOYSA-N
Compound Aliases: 3-MATIDA

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
44266 BRD-A87125127 A375 10 uM 6 h 0.21 0.87 0.01 0.0 0.0 0.0
44497 BRD-A87125127 A549 10 uM 24 h 0.0 0.0 0.0 0.36 1.28 1.37
44793 BRD-A87125127 ASC 10 uM 24 h -0.24 -0.99 0.13 0.0 0.0 0.0
45114 BRD-A87125127 HEPG2 10 uM 6 h 0.19 0.79 0.0 0.0 0.0 0.0
45385 BRD-A87125127 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45624 BRD-A87125127 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.26 -0.89 0.26
45913 BRD-A87125127 NPC 10 uM 24 h 0.0 0.0 0.0 0.35 1.24 1.25
46230 BRD-A87125127 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).