CMap Candidate Details

Structure:
CMap ID: C02121
Pert ID: BRD-A87130939
Compound Name: masoprocol
Targets: ALOX5
MoA: Lipoxygenase inhibitor
SMILES: CC(Cc1ccc(O)c(O)c1)C(C)Cc1ccc(O)c(O)c1
InchiKey: HCZKYJDFEPMADG-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
95306 BRD-A87130939 A549 10 uM 24 h 0.24 1.01 0.12 0.0 0.0 0.0
95351 BRD-A87130939 MCF??7.00 10 uM 24 h -0.17 -0.72 0.0 0.0 0.0 0.0
95464 BRD-A87130939 U2OS 10 uM 6 h 0.0 0.0 0.0 0.26 0.91 0.24
125575 BRD-A87130939 A375 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125627 BRD-A87130939 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125646 BRD-A87130939 HEK293 10 uM 24 h -0.29 -1.21 0.58 0.0 0.0 0.0
125724 BRD-A87130939 HUVEC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125771 BRD-A87130939 JURKAT 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125798 BRD-A87130939 MCF10A 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125870 BRD-A87130939 PC3 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125923 BRD-A87130939 YAPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133759 BRD-A87130939 HELA 2.22 uM 24 h -0.2 -0.83 0.0 0.0 0.0 0.0
133792 BRD-A87130939 HT29 2.22 uM 24 h -0.29 -1.2 0.55 0.24 0.85 0.14
133907 BRD-A87130939 MDAMB231 0.74 uM 24 h 0.0 0.0 0.0 -0.25 -0.85 0.2
133972 BRD-A87130939 THP1 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).