CMap Candidate Details

Structure:
CMap ID: C21226
Pert ID: BRD-K59256312
Compound Name: gabexate
Targets: PRSS1
MoA: Serine protease inhibitor
SMILES: CCOC(=O)c1ccc(OC(=O)CCCCCNC(N)=N)cc1
InchiKey: YKGYIDJEEQRWQH-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
2907 BRD-K59256312 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.32 -1.06 0.74
3382 BRD-K59256312 HCC515 10 uM 6 h 0.25 1.06 0.19 0.0 0.0 0.0
3837 BRD-K59256312 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
24590 BRD-K59256312 A549 10 uM 24 h -0.29 -1.19 0.53 -0.26 -0.88 0.26
44422 BRD-K59256312 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44994 BRD-K59256312 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
45286 BRD-K59256312 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45550 BRD-K59256312 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45834 BRD-K59256312 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
46110 BRD-K59256312 NPC 10 uM 24 h 0.23 0.96 0.08 0.0 0.0 0.0
46423 BRD-K59256312 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46749 BRD-K59256312 SKB 10 uM 24 h 0.0 0.0 0.0 0.3 1.07 0.64
52314 BRD-K59256312 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).