CMap Candidate Details

Structure:
CMap ID: C21243
Pert ID: BRD-K59325863
Compound Name: delanzomib
Targets: --
MoA: --
SMILES: CC(C)C[C@H](NC(=O)[C@@H](NC(=O)c1cccc(n1)-c1ccccc1)[C@@H](C)O)B(O)O
InchiKey: SJFBTAPEPRWNKH-CCKFTAQKSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
95307 BRD-K59325863 A549 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
95432 BRD-K59325863 U2OS 0.08 uM 48 h 0.24 0.99 0.09 0.0 0.0 0.0
96417 BRD-K59325863 PC3 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123587 BRD-K59325863 HEK293 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123702 BRD-K59325863 MCF10A 3.33 uM 24 h 0.21 0.88 0.02 0.0 0.0 0.0
123729 BRD-K59325863 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123772 BRD-K59325863 YAPC 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131991 BRD-K59325863 A375 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132019 BRD-K59325863 HA1E 0.01 uM 24 h 0.25 1.06 0.19 0.0 0.0 0.0
132044 BRD-K59325863 HELA 0.01 uM 24 h 0.24 1.0 0.11 0.0 0.0 0.0
132062 BRD-K59325863 HT29 0.01 uM 24 h 0.0 0.0 0.0 -0.32 -1.09 0.82
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).