CMap Candidate Details

Structure:
CMap ID: C21245
Pert ID: BRD-K59331299
Compound Name: voglibose
Targets: GAA; MGAM
MoA: Glucosidase inhibitor
SMILES: OCC(CO)N[C@H]1C[C@@](O)(CO)[C@@H](O)[C@H](O)[C@H]1O
InchiKey: FZNCGRZWXLXZSZ-GENCIFFESA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
123808 BRD-K59331299 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123849 BRD-K59331299 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123875 BRD-K59331299 HA1E 0.125 uM 24 h -0.22 -0.93 0.07 0.0 0.0 0.0
123915 BRD-K59331299 HEK293 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124017 BRD-K59331299 JURKAT 0.04 uM 24 h 0.0 0.0 0.0 -0.37 -1.23 1.28
124069 BRD-K59331299 MCF10A 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124136 BRD-K59331299 MDAMB231 10 uM 24 h 0.21 0.88 0.01 0.28 0.98 0.37
124199 BRD-K59331299 THP1 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124251 BRD-K59331299 YAPC 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132203 BRD-K59331299 HELA 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132239 BRD-K59331299 HT29 0.74 uM 24 h 0.27 1.15 0.32 0.24 0.84 0.12
132263 BRD-K59331299 MCF??7.00 0.74 uM 24 h -0.27 -1.11 0.36 0.23 0.83 0.12
132307 BRD-K59331299 PC3 2.22 uM 24 h -0.26 -1.09 0.32 -0.28 -0.95 0.4
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).