CMap Candidate Details

Structure:
CMap ID: C02126
Pert ID: BRD-A87435144
Compound Name: AZD-7545
Targets: --
MoA: --
SMILES: CN(C)C(=O)c1ccc(cc1)S(=O)(=O)c1ccc(NC(=O)C(C)(O)C(F)(F)F)c(Cl)c1
InchiKey: DTDZLJHKVNTQGZ-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
127723 BRD-A87435144 A375 10 uM 24 h 0.22 0.92 0.04 0.0 0.0 0.0
127764 BRD-A87435144 A549 10 uM 24 h -0.27 -1.11 0.36 -0.27 -0.9 0.28
127839 BRD-A87435144 HEK293 3.33 uM 24 h 0.0 0.0 0.0 0.2 0.72 0.02
127892 BRD-A87435144 HT29 0.04 uM 24 h -0.25 -1.06 0.25 -0.32 -1.08 0.81
127913 BRD-A87435144 HUVEC 0.37 uM 24 h 0.35 1.47 1.12 0.26 0.94 0.28
127969 BRD-A87435144 MCF10A 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128018 BRD-A87435144 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.32 1.13 0.84
128036 BRD-A87435144 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135517 BRD-A87435144 HA1E 0.03 uM 24 h -0.26 -1.09 0.32 0.24 0.85 0.14
135540 BRD-A87435144 HELA 2.22 uM 24 h -0.24 -1.01 0.15 0.0 0.0 0.0
135632 BRD-A87435144 JURKAT 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135732 BRD-A87435144 YAPC 0.08 uM 24 h 0.24 0.98 0.09 0.26 0.93 0.26
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).