CMap Candidate Details

Structure:
CMap ID: C21270
Pert ID: BRD-K59419204
Compound Name: AM-281
Targets: CNR1
MoA: Cannabinoid receptor antagonist
SMILES: Cc1c(nn(c1-c1ccc(I)cc1)-c1ccc(Cl)cc1Cl)C(=O)NN1CCOCC1
InchiKey: AJFFBPZYXRNAIC-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
6900 BRD-K59419204 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
7019 BRD-K59419204 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
7474 BRD-K59419204 HA1E 10 uM 6 h 0.29 1.22 0.48 -0.33 -1.11 0.9
7699 BRD-K59419204 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
8019 BRD-K59419204 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
8169 BRD-K59419204 MCF??7.00 10 uM 6 h 0.24 1.01 0.12 -0.21 -0.72 0.04
8526 BRD-K59419204 PC3 10 uM 6 h 0.2 0.83 0.0 0.0 0.0 0.0
8714 BRD-K59419204 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).