CMap Candidate Details

Structure:
CMap ID: C21287
Pert ID: BRD-K59469039
Compound Name: AG-879
Targets: --
MoA: --
SMILES: CC(C)(C)c1cc(cc(c1O)C(C)(C)C)C=C(/C#N)C(N)=S
InchiKey: XRZYELWZLNAXGE-KPKJPENVSA-N
Compound Aliases: tyrphostin-AG-879

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1591 BRD-K59469039 HA1E 10 uM 24 h 0.25 1.06 0.18 0.0 0.0 0.0
1928 BRD-K59469039 HCC515 10 uM 24 h 0.0 0.0 0.0 -0.25 -0.83 0.16
2168 BRD-K59469039 PC3 10 uM 24 h 0.0 0.0 0.0 -0.39 -1.3 1.58
2651 BRD-K59469039 VCAP 10 uM 6 h 0.0 0.0 0.0 -0.3 -1.02 0.62
41795 BRD-K59469039 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42110 BRD-K59469039 A549 10 uM 6 h -0.22 -0.9 0.04 0.0 0.0 0.0
42402 BRD-K59469039 ASC 10 uM 24 h -0.24 -0.98 0.12 -0.3 -1.0 0.55
43021 BRD-K59469039 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43207 BRD-K59469039 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.39 -1.33 1.72
43586 BRD-K59469039 NPC 10 uM 24 h 0.26 1.1 0.24 -0.3 -1.03 0.62
53405 BRD-K59469039 HEPG2 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
53524 BRD-K59469039 HUH7 2.5 uM 24 h 0.0 0.0 0.0 -0.26 -0.89 0.27
53677 BRD-K59469039 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
99705 BRD-K59469039 U2OS 15 uM 6 h 0.0 0.0 0.0 -0.34 -1.14 1.01
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).