CMap Candidate Details

Structure:
CMap ID: C02131
Pert ID: BRD-A87606379
Compound Name: nadolol
Targets: ADRB1; ADRB2
MoA: Adrenergic receptor antagonist
SMILES: CC(C)(C)NCC(O)COc1cccc2C[C@@H](O)[C@@H](O)Cc12
InchiKey: VWPOSFSPZNDTMJ-UCWKZMIHSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5169 BRD-A87606379 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
5284 BRD-A87606379 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
5557 BRD-A87606379 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
5861 BRD-A87606379 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6496 BRD-A87606379 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
37561 BRD-A87606379 ASC 10 uM 24 h 0.0 0.0 0.0 -0.3 -1.01 0.58
38402 BRD-A87606379 NPC 10 uM 24 h 0.0 0.0 0.0 -0.3 -1.02 0.61
49964 BRD-A87606379 A549 10 uM 6 h 0.0 0.0 0.0 -0.27 -0.9 0.29
50480 BRD-A87606379 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
50643 BRD-A87606379 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.29 -0.98 0.47
50819 BRD-A87606379 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).