CMap Candidate Details

Structure:
CMap ID: C02133
Pert ID: BRD-A87719232
Compound Name: naproxen
Targets: PTGS1; PTGS2
MoA: Cyclooxygenase inhibitor
SMILES: COc1ccc2cc(ccc2c1)C(C)C(=O)O
InchiKey: CMWTZPSULFXXJA-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1518 BRD-A87719232 HA1E 10 uM 24 h 0.21 0.87 0.01 -0.28 -0.94 0.37
2058 BRD-A87719232 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
2354 BRD-A87719232 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
2504 BRD-A87719232 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41689 BRD-A87719232 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42034 BRD-A87719232 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42239 BRD-A87719232 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42885 BRD-A87719232 HT29 10 uM 6 h 0.23 0.95 0.07 0.0 0.0 0.0
43273 BRD-A87719232 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43437 BRD-A87719232 NPC 10 uM 24 h 0.0 0.0 0.0 -0.28 -0.93 0.35
43746 BRD-A87719232 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).