CMap Candidate Details

Structure:
CMap ID: C02135
Pert ID: BRD-A87983072
Compound Name: benzotript
Targets: CCKAR; CCKBR
MoA: CCK receptor antagonist
SMILES: OC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)c1ccc(Cl)cc1
InchiKey: QJERBBQXOMUURJ-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
121745 BRD-A87983072 HA1E 10 uM 24 h 0.25 1.05 0.16 0.28 0.99 0.41
121776 BRD-A87983072 HELA 10 uM 24 h 0.21 0.88 0.01 0.0 0.0 0.0
121809 BRD-A87983072 HT29 0.37 uM 24 h 0.0 0.0 0.0 0.29 1.01 0.45
121853 BRD-A87983072 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121876 BRD-A87983072 YAPC 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129771 BRD-A87983072 A375 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129851 BRD-A87983072 HEK293 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129928 BRD-A87983072 JURKAT 0.08 uM 24 h -0.25 -1.04 0.22 -0.3 -1.01 0.58
129976 BRD-A87983072 MCF10A 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130012 BRD-A87983072 MCF??7.00 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130062 BRD-A87983072 MDAMB231 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130133 BRD-A87983072 THP1 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).