CMap Candidate Details

Structure:
CMap ID: C21350
Pert ID: BRD-K59650319
Compound Name: YM-298198
Targets: GRM1
MoA: Glutamate receptor antagonist
SMILES: CN(C1CCCCC1)C(=O)c1sc2nc3ccc(N)cc3n2c1C
InchiKey: KCBXOMYXOBVLED-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1760 BRD-K59650319 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
1929 BRD-K59650319 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
2403 BRD-K59650319 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
2673 BRD-K59650319 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
41796 BRD-K59650319 A375 10 uM 6 h 0.0 0.0 0.0 -0.27 -0.91 0.31
42111 BRD-K59650319 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42404 BRD-K59650319 ASC 10 uM 24 h 0.0 0.0 0.0 0.22 0.76 0.05
42722 BRD-K59650319 HEPG2 10 uM 6 h -0.28 -1.15 0.45 0.0 0.0 0.0
43022 BRD-K59650319 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43208 BRD-K59650319 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.29 -0.99 0.51
43891 BRD-K59650319 PHH 10 uM 24 h -0.21 -0.87 0.02 0.0 0.0 0.0
44147 BRD-K59650319 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
98238 BRD-K59650319 NPC 10 uM 6 h 0.0 0.0 0.0 0.27 0.94 0.3
98407 BRD-K59650319 NEU 10 uM 24 h 0.3 1.25 0.56 -0.29 -0.98 0.48
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).