CMap Candidate Details

Structure:
CMap ID: C02137
Pert ID: BRD-A88080608
Compound Name: equilin
Targets: HSD17B1
MoA: Estrogen receptor agonist
SMILES: CC12CCC3C(=CCc4cc(O)ccc34)C1CCC2=O
InchiKey: WKRLQDKEXYKHJB-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1192 BRD-A88080608 PC3 0.12 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
1241 BRD-A88080608 A549 10 uM 48 h 0.0 0.0 0.0 0.0 0.0 0.0
1280 BRD-A88080608 MCF??7.00 1.11 uM 48 h 0.0 0.0 0.0 0.0 0.0 0.0
1379 BRD-A88080608 U2OS 0.12 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
5285 BRD-A88080608 HA1E 10 uM 24 h 0.0 0.0 0.0 0.27 0.94 0.3
5558 BRD-A88080608 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
5862 BRD-A88080608 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6497 BRD-A88080608 VCAP 10 uM 6 h 0.0 0.0 0.0 0.25 0.87 0.18
41690 BRD-A88080608 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42886 BRD-A88080608 HT29 10 uM 6 h 0.0 0.0 0.0 0.28 1.0 0.43
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).