CMap Candidate Details

Structure:
CMap ID: C02138
Pert ID: BRD-A88138582
Compound Name: halcinonide
Targets: NR3C1
MoA: Glucocorticoid receptor agonist
SMILES: CC1(C)O[C@@H]2CC3C4CCC5=CC(=O)CCC5(C)C4(F)C(O)CC3(C)[C@@]2(O1)C(=O)CCl
InchiKey: MUQNGPZZQDCDFT-RLDTZFIDSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
127725 BRD-A88138582 A375 10 uM 24 h 0.0 0.0 0.0 0.31 1.09 0.68
127765 BRD-A88138582 A549 0.125 uM 24 h 0.0 0.0 0.0 -0.34 -1.15 1.06
127808 BRD-A88138582 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.26 -0.87 0.22
127842 BRD-A88138582 HEK293 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127916 BRD-A88138582 HUVEC 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127970 BRD-A88138582 MCF10A 10 uM 24 h -0.26 -1.07 0.28 0.0 0.0 0.0
128039 BRD-A88138582 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135543 BRD-A88138582 HELA 0.03 uM 24 h 0.0 0.0 0.0 -0.35 -1.19 1.15
135595 BRD-A88138582 HT29 0.03 uM 24 h -0.21 -0.89 0.03 0.0 0.0 0.0
135634 BRD-A88138582 JURKAT 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135684 BRD-A88138582 MCF??7.00 2.22 uM 24 h 0.28 1.15 0.33 0.0 0.0 0.0
135733 BRD-A88138582 YAPC 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).