CMap Candidate Details

Structure:
CMap ID: C21421
Pert ID: BRD-K59875992
Compound Name: FPL-62064
Targets: --
MoA: --
SMILES: COc1ccc(Nc2ccn(n2)-c2ccccc2)cc1
InchiKey: WKLGNFJHVJIZPK-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
95548 BRD-K59875992 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
95682 BRD-K59875992 U2OS 0.12 uM 48 h 0.0 0.0 0.0 0.0 0.0 0.0
96358 BRD-K59875992 A375 3.33 uM 24 h 0.0 0.0 0.0 -0.17 -0.56 0.0
96429 BRD-K59875992 PC3 3.33 uM 24 h -0.28 -1.16 0.46 -0.29 -0.98 0.48
123919 BRD-K59875992 HEK293 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124021 BRD-K59875992 JURKAT 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124072 BRD-K59875992 MCF10A 1.11 uM 24 h -0.27 -1.14 0.42 -0.28 -0.93 0.34
124139 BRD-K59875992 MDAMB231 1.11 uM 24 h -0.22 -0.92 0.06 0.0 0.0 0.0
124202 BRD-K59875992 THP1 3.33 uM 24 h -0.19 -0.79 0.0 0.38 1.35 1.72
124255 BRD-K59875992 YAPC 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132176 BRD-K59875992 HA1E 2.22 uM 24 h 0.29 1.22 0.48 0.0 0.0 0.0
132207 BRD-K59875992 HELA 0.74 uM 24 h -0.2 -0.82 0.0 0.24 0.84 0.13
132240 BRD-K59875992 HT29 2.22 uM 24 h 0.0 0.0 0.0 0.27 0.95 0.31
132264 BRD-K59875992 MCF??7.00 0.03 uM 24 h -0.24 -1.02 0.18 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).