CMap Candidate Details

Structure:
CMap ID: C21448
Pert ID: BRD-K59962020
Compound Name: CHEMBL-374350
Targets: --
MoA: --
SMILES: Cc1cc2nc(NCCCO)n(CC(=O)c3cc(c(O)c(c3)C(C)(C)C)C(C)(C)C)c2cc1C
InchiKey: CYCGGKILBWERDJ-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
9459 BRD-K59962020 AGS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10067 BRD-K59962020 HA1E 10 uM 6 h 0.0 0.0 0.0 0.26 0.92 0.25
10237 BRD-K59962020 HCC515 10 uM 24 h 0.0 0.0 0.0 -0.23 -0.78 0.09
10550 BRD-K59962020 HCT116 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10988 BRD-K59962020 HT29 10 uM 24 h 0.15 0.61 0.0 0.21 0.74 0.03
11525 BRD-K59962020 NCIH2073 10 uM 6 h -0.24 -0.99 0.14 0.0 0.0 0.0
11795 BRD-K59962020 NCIH508 10 uM 6 h 0.22 0.9 0.03 0.26 0.91 0.23
12087 BRD-K59962020 NCIH596 10 uM 6 h 0.0 0.0 0.0 0.3 1.06 0.61
12346 BRD-K59962020 NOMO1 10 uM 6 h -0.22 -0.94 0.07 0.34 1.2 1.07
12616 BRD-K59962020 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12824 BRD-K59962020 SW480 10 uM 6 h 0.24 1.01 0.11 0.29 1.04 0.53
13096 BRD-K59962020 THP1 10 uM 6 h 0.0 0.0 0.0 0.43 1.54 2.3
13313 BRD-K59962020 U937 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13644 BRD-K59962020 VCAP 10 uM 6 h 0.0 0.0 0.0 0.32 1.14 0.85
21833 BRD-K59962020 A375 10 uM 6 h 0.0 0.0 0.0 -0.32 -1.08 0.79
22145 BRD-K59962020 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
23106 BRD-K59962020 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
23743 BRD-K59962020 MCF??7.00 10 uM 6 h -0.23 -0.97 0.1 0.22 0.79 0.07
115140 BRD-K59962020 U2OS 20 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).