CMap Candidate Details

Structure:
CMap ID: C02155
Pert ID: BRD-A89049230
Compound Name: BRD-A89049230
Targets: TSHR
MoA: Thyroid hormone stimulant
SMILES: COc1ccc(cc1COc1ccc(NC(C)=O)cc1)C1Nc2cccc(O)c2C(=O)N1Cc1ccccc1
InchiKey: JRVXFGNCHKHBPA-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
22074 BRD-A89049230 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
22104 BRD-A89049230 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
22406 BRD-A89049230 HA1E 10 uM 6 h 0.0 0.0 0.0 -0.27 -0.91 0.31
22668 BRD-A89049230 HCC515 10 uM 6 h 0.0 0.0 0.0 0.32 1.12 0.76
22951 BRD-A89049230 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
23258 BRD-A89049230 HT29 10 uM 6 h 0.0 0.0 0.0 0.33 1.18 0.99
23529 BRD-A89049230 MCF??7.00 10 uM 24 h -0.25 -1.04 0.22 0.0 0.0 0.0
23801 BRD-A89049230 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
24095 BRD-A89049230 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
114980 BRD-A89049230 U2OS 20 uM 6 h -0.19 -0.8 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).