CMap Candidate Details

Structure:
CMap ID: C21556
Pert ID: BRD-K60274257
Compound Name: dephostatin
Targets: PTPN1; PTPN6
MoA: Tyrosine phosphatase inhibitor
SMILES: CN([N+][O-])c1cc(O)ccc1O
InchiKey: HCJOLYFWJWJPTJ-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5220 BRD-K60274257 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
5346 BRD-K60274257 HA1E 10 uM 24 h 0.23 0.94 0.06 0.0 0.0 0.0
5657 BRD-K60274257 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
5935 BRD-K60274257 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.25 -0.83 0.16
6042 BRD-K60274257 HT29 10 uM 6 h 0.0 0.0 0.0 -0.34 -1.15 1.07
6205 BRD-K60274257 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
6316 BRD-K60274257 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39466 BRD-K60274257 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39722 BRD-K60274257 ASC 10 uM 24 h -0.2 -0.82 0.0 0.0 0.0 0.0
40624 BRD-K60274257 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40835 BRD-K60274257 NEU 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41141 BRD-K60274257 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41478 BRD-K60274257 SKB 10 uM 24 h 0.0 0.0 0.0 0.24 0.84 0.13
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).