CMap Candidate Details

Structure:
CMap ID: C02159
Pert ID: BRD-A89175223
Compound Name: bisoprolol
Targets: ADRB1
MoA: Adrenergic receptor antagonist
SMILES: CC(C)NCC(O)COc1ccc(COCCOC(C)C)cc1
InchiKey: VHYCDWMUTMEGQY-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5559 BRD-A89175223 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
25310 BRD-A89175223 VCAP 10 uM 24 h 0.0 0.0 0.0 -0.26 -0.88 0.24
37562 BRD-A89175223 ASC 10 uM 24 h 0.0 0.0 0.0 -0.27 -0.92 0.33
37861 BRD-A89175223 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.42 -1.4 2.02
38403 BRD-A89175223 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38894 BRD-A89175223 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127349 BRD-A89175223 A375 0.125 uM 24 h -0.23 -0.96 0.1 0.0 0.0 0.0
127389 BRD-A89175223 A549 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127422 BRD-A89175223 HA1E 0.04 uM 24 h -0.21 -0.89 0.04 0.0 0.0 0.0
127463 BRD-A89175223 HELA 3.33 uM 24 h 0.28 1.16 0.36 0.0 0.0 0.0
127512 BRD-A89175223 JURKAT 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127572 BRD-A89175223 MCF??7.00 1.11 uM 24 h -0.29 -1.19 0.55 0.0 0.0 0.0
127604 BRD-A89175223 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127644 BRD-A89175223 THP1 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127682 BRD-A89175223 YAPC 0.125 uM 24 h -0.18 -0.76 0.0 0.27 0.96 0.34
135399 BRD-A89175223 HT29 2.22 uM 24 h 0.0 0.0 0.0 -0.37 -1.26 1.35
135437 BRD-A89175223 MCF10A 0.08 uM 24 h 0.0 0.0 0.0 0.35 1.22 1.18
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).