CMap Candidate Details

Structure:
CMap ID: C02164
Pert ID: BRD-A89337244
Compound Name: PD-102807
Targets: CHRM4
MoA: Acetylcholine receptor antagonist
SMILES: CCOC(=O)c1c(C)[nH]c2ccc3OC4N(CCc5cc(OC)ccc45)Cc3c12
InchiKey: VDDUJINYXKGZLV-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
2977 BRD-A89337244 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
3327 BRD-A89337244 HCC515 10 uM 6 h 0.0 0.0 0.0 0.28 1.01 0.44
3457 BRD-A89337244 PC3 10 uM 24 h 0.0 0.0 0.0 -0.39 -1.31 1.71
3709 BRD-A89337244 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44267 BRD-A89337244 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44498 BRD-A89337244 A549 10 uM 24 h 0.0 0.0 0.0 -0.27 -0.9 0.28
44794 BRD-A89337244 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
45115 BRD-A89337244 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45386 BRD-A89337244 HT29 10 uM 6 h 0.0 0.0 0.0 0.45 1.61 2.38
45625 BRD-A89337244 MCF??7.00 10 uM 24 h -0.2 -0.82 0.0 -0.29 -0.96 0.44
45914 BRD-A89337244 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46231 BRD-A89337244 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46545 BRD-A89337244 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).