CMap Candidate Details

Structure:
CMap ID: C21643
Pert ID: BRD-K60585088
Compound Name: paricalcitol
Targets: VDR
MoA: Vitamin D receptor agonist
SMILES: C[C@H](C=C[C@H](C)C(C)(C)O)[C@H]1CC[C@@H]2[C@]1(C)CCCC2=C/C=C1C[C@@H](O)C[C@H](O)C1
InchiKey: BPKAHTKRCLCHEA-UBFJEZKGSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
123540 BRD-K60585088 HA1E 3.33 uM 24 h 0.0 0.0 0.0 0.31 1.1 0.68
123577 BRD-K60585088 HEK293 0.125 uM 24 h -0.28 -1.17 0.5 -0.24 -0.8 0.12
123652 BRD-K60585088 HT29 10 uM 24 h 0.23 0.97 0.08 0.0 0.0 0.0
123694 BRD-K60585088 MCF10A 10 uM 24 h 0.0 0.0 0.0 -0.3 -1.0 0.54
123725 BRD-K60585088 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.25 -0.84 0.18
123743 BRD-K60585088 PC3 0.125 uM 24 h -0.27 -1.11 0.36 0.0 0.0 0.0
131984 BRD-K60585088 A375 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132038 BRD-K60585088 HELA 2.22 uM 24 h 0.0 0.0 0.0 0.31 1.09 0.67
132141 BRD-K60585088 YAPC 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).