CMap Candidate Details

Structure:
CMap ID: C21650
Pert ID: BRD-K60623809
Compound Name: SU-11652
Targets: KDR; PDGFRB
MoA: Tyrosine kinase inhibitor
SMILES: CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C/2C(=O)Nc3ccc(Cl)cc23)c1C
InchiKey: XPLJEFSRINKZLC-ATVHPVEESA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
9215 BRD-K60623809 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9767 BRD-K60623809 H1299 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10337 BRD-K60623809 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10551 BRD-K60623809 HCT116 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11107 BRD-K60623809 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11286 BRD-K60623809 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11527 BRD-K60623809 NCIH2073 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12617 BRD-K60623809 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12826 BRD-K60623809 SW480 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13646 BRD-K60623809 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
97305 BRD-K60623809 HAP1 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
98763 BRD-K60623809 NPC 10 uM 24 h 0.0 0.0 0.0 0.28 0.98 0.39
99066 BRD-K60623809 NEU 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
121573 BRD-K60623809 A375 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121619 BRD-K60623809 HA1E 3.33 uM 24 h 0.31 1.28 0.61 0.0 0.0 0.0
129613 BRD-K60623809 HELA 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129740 BRD-K60623809 YAPC 0.74 uM 24 h 0.22 0.9 0.02 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).