CMap Candidate Details

Structure:
CMap ID: C21833
Pert ID: BRD-K61106942
Compound Name: BRD-K61106942
Targets: PKM
MoA: Pyruvate kinase isozyme activator
SMILES: Clc1cccc(NS(=O)(=O)c2ccc3NC(=O)CCc3c2)c1
InchiKey: KQHKZXBKJWOHHU-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
21878 BRD-K61106942 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
22315 BRD-K61106942 A549 10 uM 6 h 0.0 0.0 0.0 -0.29 -0.99 0.51
22532 BRD-K61106942 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
22811 BRD-K61106942 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
23109 BRD-K61106942 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
23399 BRD-K61106942 HT29 10 uM 6 h 0.0 0.0 0.0 -0.35 -1.17 1.12
23608 BRD-K61106942 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
24016 BRD-K61106942 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
24185 BRD-K61106942 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).