CMap Candidate Details

Structure:
CMap ID: C02184
Pert ID: BRD-A90131694
Compound Name: alclometasone
Targets: NR3C1
MoA: Glucocorticoid receptor agonist
SMILES: CCC(=O)OCC(=O)[C@@]1(OC(=O)CC)[C@H](C)CC2C3[C@H](Cl)CC4=CC(=O)C=C[C@]4(C)C3[C@@H](O)C[C@@]21C
InchiKey: DJHCCTTVDRAMEH-PEDQINGESA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5286 BRD-A90131694 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.3 -1.01 0.58
5740 BRD-A90131694 HCC515 10 uM 6 h -0.19 -0.8 0.0 -0.32 -1.06 0.75
5863 BRD-A90131694 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
5995 BRD-A90131694 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6079 BRD-A90131694 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6252 BRD-A90131694 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6411 BRD-A90131694 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37109 BRD-A90131694 A375 10 uM 6 h 0.0 0.0 0.0 -0.32 -1.07 0.78
37258 BRD-A90131694 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37563 BRD-A90131694 ASC 10 uM 24 h 0.0 0.0 0.0 -0.34 -1.15 1.07
38404 BRD-A90131694 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38895 BRD-A90131694 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).