CMap Candidate Details

Structure:
CMap ID: C21854
Pert ID: BRD-K61175124
Compound Name: BRD-K61175124
Targets: --
MoA: --
SMILES: COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5cccc(c5)N6CCC6=O)c7ccccc73
InchiKey: FTKXCBYAQTWBTF-HSLFHSRNSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
29899 BRD-K61175124 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
30223 BRD-K61175124 A549 10 uM 6 h -0.28 -1.15 0.44 0.0 0.0 0.0
30497 BRD-K61175124 ASC 10 uM 24 h 0.21 0.89 0.02 0.0 0.0 0.0
30796 BRD-K61175124 HA1E 10 uM 6 h 0.0 0.0 0.0 0.33 1.15 0.9
31089 BRD-K61175124 HCC515 10 uM 6 h 0.0 0.0 0.0 -0.21 -0.7 0.03
31397 BRD-K61175124 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.22 -0.73 0.05
31667 BRD-K61175124 HT29 10 uM 6 h -0.31 -1.29 0.77 0.0 0.0 0.0
31898 BRD-K61175124 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
32476 BRD-K61175124 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
32804 BRD-K61175124 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
33079 BRD-K61175124 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
33321 BRD-K61175124 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).