CMap Candidate Details

Structure:
CMap ID: C02187
Pert ID: BRD-A90311807
Compound Name: cilastatin
Targets: DPEP1
MoA: Dehydropeptidase inhibitor
SMILES: CC1(C)CC1C(=O)NC(=CCCCCSCC(N)C(=O)O)C(=O)O
InchiKey: DHSUYTOATWAVLW-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1713 BRD-A90311807 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
1854 BRD-A90311807 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
2268 BRD-A90311807 PC3 10 uM 24 h -0.18 -0.75 0.0 0.36 1.26 1.29
2748 BRD-A90311807 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39078 BRD-A90311807 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39290 BRD-A90311807 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39608 BRD-A90311807 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
40212 BRD-A90311807 HT29 10 uM 6 h -0.22 -0.93 0.07 0.0 0.0 0.0
40443 BRD-A90311807 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
40731 BRD-A90311807 NEU 10 uM 24 h 0.0 0.0 0.0 -0.28 -0.94 0.38
41033 BRD-A90311807 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41356 BRD-A90311807 SKB 10 uM 24 h -0.19 -0.77 0.0 0.0 0.0 0.0
100385 BRD-A90311807 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).