CMap Candidate Details

Structure:
CMap ID: C02191
Pert ID: BRD-A90490067
Compound Name: fulvestrant
Targets: ESR1
MoA: Estrogen receptor antagonist
SMILES: CC12CCC3C(C2CCC1O)C(CCCCCCCCCS(=O)CCCC(F)(F)C(F)(F)F)Cc4cc(O)ccc34
InchiKey: VWUXBMIQPBEWFH-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1 BRD-A90490067 A375 10 uM 24 h 0.0 0.0 0.0 -0.41 -1.39 2.02
6 BRD-A90490067 NCIH2073 0.66 uM 3 h 0.0 0.0 0.0 -0.36 -1.2 1.16
14 BRD-A90490067 NCIH508 2.5 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
23 BRD-A90490067 NCIH596 10 uM 3 h 0.0 0.0 0.0 -0.48 -1.6 15.65
31 BRD-A90490067 SKBR3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
1133 BRD-A90490067 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
5417 BRD-A90490067 HA1E 10 uM 6 h 0.22 0.93 0.05 0.0 0.0 0.0
5741 BRD-A90490067 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
5864 BRD-A90490067 HEPG2 10 uM 6 h 0.22 0.92 0.04 0.0 0.0 0.0
37564 BRD-A90490067 ASC 10 uM 24 h 0.0 0.0 0.0 -0.3 -1.0 0.51
38171 BRD-A90490067 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.25 -0.85 0.2
38671 BRD-A90490067 PHH 10 uM 24 h 0.0 0.0 0.0 0.37 1.32 1.61
60469 BRD-A90490067 VCAP 10 uM 24 h 0.0 0.0 0.0 0.23 0.83 0.11
79997 BRD-A90490067 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
80580 BRD-A90490067 NEU 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
82149 BRD-A90490067 NPC 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
90442 BRD-A90490067 HL60 10 uM 2 h 0.0 0.0 0.0 0.0 0.0 0.0
90454 BRD-A90490067 HT29 10 uM 24 h -0.22 -0.93 0.07 -0.26 -0.86 0.21
100387 BRD-A90490067 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).