CMap Candidate Details

Structure:
CMap ID: C21910
Pert ID: BRD-K61341215
Compound Name: vecuronium
Targets: CHRNA2
MoA: Acetylcholine receptor antagonist
SMILES: CC(=O)O[C@H]1[C@H](C[C@@H]2[C@H]3CC[C@@H]4C[C@H](OC(C)=O)[C@H](C[C@@]4(C)[C@@H]3CC[C@@]12C)N1CCCCC1)[N+]1(C)CCCCC1
InchiKey: BGSZAXLLHYERSY-NGQATJDKSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
33538 BRD-K61341215 A375 10 uM 6 h 0.0 0.0 0.0 -0.2 -0.68 0.02
33815 BRD-K61341215 A549 10 uM 24 h 0.0 0.0 0.0 0.31 1.08 0.66
34137 BRD-K61341215 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
34650 BRD-K61341215 HCC515 10 uM 6 h 0.24 0.98 0.09 0.27 0.96 0.33
34918 BRD-K61341215 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
35169 BRD-K61341215 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
35384 BRD-K61341215 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
35810 BRD-K61341215 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
36093 BRD-K61341215 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
36296 BRD-K61341215 PHH 10 uM 24 h 0.24 1.0 0.11 0.0 0.0 0.0
36597 BRD-K61341215 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
36842 BRD-K61341215 VCAP 10 uM 24 h -0.18 -0.74 0.0 -0.17 -0.58 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).