CMap Candidate Details
Structure:
| CMap ID: | C21958 |
| Pert ID: | BRD-K61468417 |
| Compound Name: | doxorubicin |
| Targets: | TOP2A |
| MoA: | Topoisomerase inhibitor |
| SMILES: | COc1cccc2C(=O)c3c(O)c4C[C@](O)(C[C@@H](O[C@H]5C[C@H](N)[C@H](O)[C@H](C)O5)c4c(O)c3C(=O)c12)C(=O)CO |
| InchiKey: | AOJJSUZBOXZQNB-HEKDSCCBSA-N |
| Compound Aliases: | -- |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 95541 | BRD-K61468417 | A549 | 10 uM | 6 h | -0.25 | -1.03 | 0.2 | 0.0 | 0.0 | 0.0 |
| 95584 | BRD-K61468417 | MCF??7.00 | 1.11 uM | 48 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 95628 | BRD-K61468417 | U2OS | 0.12 uM | 24 h | -0.2 | -0.84 | 0.0 | -0.3 | -1.0 | 0.53 |