CMap Candidate Details

Structure:
CMap ID: C22022
Pert ID: BRD-K61662457
Compound Name: CAY-10594
Targets: PLD2
MoA: Phospholipase inhibitor
SMILES: O=C(NCCN1CCC2(CC1)N(CNC2=O)c1ccccc1)c1ccc2ccccc2c1
InchiKey: FAIFAFUXFFWVNQ-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
8964 BRD-K61662457 A375 20 uM 24 h -0.25 -1.06 0.25 0.41 1.46 2.23
9217 BRD-K61662457 A549 20 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9465 BRD-K61662457 AGS 20 uM 6 h 0.0 0.0 0.0 0.25 0.88 0.19
9772 BRD-K61662457 H1299 20 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9890 BRD-K61662457 HA1E 20 uM 24 h 0.0 0.0 0.0 0.33 1.16 0.9
10555 BRD-K61662457 HCT116 20 uM 6 h 0.0 0.0 0.0 0.29 1.02 0.47
10993 BRD-K61662457 HT29 20 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
11287 BRD-K61662457 MCF??7.00 20 uM 6 h -0.2 -0.83 0.0 0.0 0.0 0.0
11531 BRD-K61662457 NCIH2073 20 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11800 BRD-K61662457 NCIH508 20 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12094 BRD-K61662457 NCIH596 20 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12353 BRD-K61662457 NOMO1 20 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12961 BRD-K61662457 THP1 20 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13318 BRD-K61662457 U937 20 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13650 BRD-K61662457 VCAP 20 uM 6 h -0.16 -0.68 0.0 0.4 1.43 2.2
96909 BRD-K61662457 PC3 10 uM 24 h 0.0 0.0 0.0 0.39 1.37 2.08
116104 BRD-K61662457 HCC515 10 uM 24 h 0.21 0.87 0.01 0.0 0.0 0.0
116149 BRD-K61662457 HEPG2 10 uM 24 h 0.26 1.1 0.24 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).