CMap Candidate Details

Structure:
CMap ID: C22032
Pert ID: BRD-K61691541
Compound Name: PF-03084014
Targets: --
MoA: --
SMILES: CCC[C@H](N[C@H]1CCc2cc(F)cc(F)c2C1)C(=O)Nc1cn(cn1)C(C)(C)CNCC(C)(C)C
InchiKey: VFCRKLWBYMDAED-REWPJTCUSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
124605 BRD-K61691541 A549 0.04 uM 24 h 0.0 0.0 0.0 0.37 1.3 1.59
124632 BRD-K61691541 HA1E 0.04 uM 24 h -0.19 -0.8 0.0 0.0 0.0 0.0
124676 BRD-K61691541 HELA 10 uM 24 h 0.27 1.14 0.31 0.0 0.0 0.0
124711 BRD-K61691541 HT29 1.11 uM 24 h 0.0 0.0 0.0 0.23 0.8 0.08
124737 BRD-K61691541 JURKAT 0.04 uM 24 h 0.22 0.9 0.02 0.0 0.0 0.0
124771 BRD-K61691541 MCF??7.00 0.04 uM 24 h -0.19 -0.81 0.0 0.0 0.0 0.0
124819 BRD-K61691541 MDAMB231 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124862 BRD-K61691541 PC3 0.125 uM 24 h 0.19 0.81 0.0 0.0 0.0 0.0
124902 BRD-K61691541 THP1 0.04 uM 24 h 0.0 0.0 0.0 -0.26 -0.86 0.22
124925 BRD-K61691541 YAPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132675 BRD-K61691541 A375 0.01 uM 24 h 0.0 0.0 0.0 -0.3 -1.01 0.56
132776 BRD-K61691541 HEK293 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132890 BRD-K61691541 MCF10A 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).