CMap Candidate Details

Structure:
CMap ID: C02205
Pert ID: BRD-A91452556
Compound Name: estradiol-cypionate
Targets: ESR1
MoA: Estrogen receptor agonist
SMILES: C[C@]12CCC3C(CCc4cc(O)ccc34)C1CC[C@@H]2OC(=O)CCC1CCCC1
InchiKey: UOACKFBJUYNSLK-OCTSOESTSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1206 BRD-A91452556 PC3 0.12 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
1229 BRD-A91452556 A549 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
1272 BRD-A91452556 MCF??7.00 10 uM 24 h -0.29 -1.21 0.57 0.0 0.0 0.0
1357 BRD-A91452556 U2OS 1.11 uM 48 h 0.0 0.0 0.0 0.0 0.0 0.0
5171 BRD-A91452556 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
5287 BRD-A91452556 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
5743 BRD-A91452556 HCC515 10 uM 6 h 0.0 0.0 0.0 -0.27 -0.92 0.34
5865 BRD-A91452556 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6499 BRD-A91452556 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44795 BRD-A91452556 ASC 10 uM 24 h 0.17 0.7 0.0 0.0 0.0 0.0
45387 BRD-A91452556 HT29 10 uM 6 h 0.0 0.0 0.0 -0.33 -1.11 0.89
45915 BRD-A91452556 NPC 10 uM 24 h 0.0 0.0 0.0 -0.24 -0.8 0.12
46232 BRD-A91452556 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).