CMap Candidate Details

Structure:
CMap ID: C22121
Pert ID: BRD-K61993165
Compound Name: niacin
Targets: HCAR2; HCAR3
MoA: Vitamin B; NAD precursor with lipid lowering effects
SMILES: OC(=O)c1cccnc1SCCc2ccccc2
InchiKey: UZERZZRWECLIKE-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
21873 BRD-K61993165 A375 10 uM 6 h 0.0 0.0 0.0 -0.31 -1.04 0.66
22147 BRD-K61993165 A549 10 uM 24 h -0.24 -1.01 0.16 0.0 0.0 0.0
22812 BRD-K61993165 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
23111 BRD-K61993165 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.24 0.84 0.12
23401 BRD-K61993165 HT29 10 uM 6 h -0.26 -1.06 0.26 0.26 0.93 0.27
23745 BRD-K61993165 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 -0.2 -0.67 0.01
24017 BRD-K61993165 PC3 10 uM 6 h 0.0 0.0 0.0 -0.26 -0.88 0.25
24333 BRD-K61993165 VCAP 10 uM 6 h 0.0 0.0 0.0 0.27 0.96 0.33
115148 BRD-K61993165 U2OS 20 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).