CMap Candidate Details

Structure:
CMap ID: C22129
Pert ID: BRD-K62012036
Compound Name: acitretin
Targets: RARA; RXRG
MoA: Retinoid receptor agonist
SMILES: COc1cc(C)c(C=CC(C)=CC=CC(C)=CC(O)=O)c(C)c1C
InchiKey: IHUNBGSDBOWDMA-AQFIFDHZSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
33665 BRD-K62012036 A375 10 uM 6 h -0.23 -0.96 0.1 -0.36 -1.23 1.25
33818 BRD-K62012036 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
34140 BRD-K62012036 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
34391 BRD-K62012036 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
34653 BRD-K62012036 HCC515 10 uM 6 h 0.29 1.21 0.44 0.32 1.12 0.78
34921 BRD-K62012036 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
35172 BRD-K62012036 HT29 10 uM 6 h 0.0 0.0 0.0 -0.24 -0.82 0.15
35445 BRD-K62012036 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
35591 BRD-K62012036 NEU 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
35975 BRD-K62012036 PC3 10 uM 24 h 0.0 0.0 0.0 -0.34 -1.14 1.01
36299 BRD-K62012036 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
36600 BRD-K62012036 SKB 10 uM 24 h 0.0 0.0 0.0 -0.25 -0.84 0.18
36845 BRD-K62012036 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
99170 BRD-K62012036 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).