CMap Candidate Details

Structure:
CMap ID: C22141
Pert ID: BRD-K62056274
Compound Name: N-methylquipazine
Targets: HTR3B; HTR2A; HTR3A
MoA: Serotonin receptor agonist
SMILES: CN1CCN(CC1)c1ccc2ccccc2n1
InchiKey: HOMWNUXPSJQSSU-UHFFFAOYSA-N
Compound Aliases: n-methylquipazine

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
6901 BRD-K62056274 A375 10 uM 6 h 0.0 0.0 0.0 -0.42 -1.42 2.04
7187 BRD-K62056274 A549 10 uM 6 h 0.18 0.75 0.0 0.0 0.0 0.0
7350 BRD-K62056274 HA1E 10 uM 24 h 0.17 0.71 0.0 -0.29 -0.96 0.43
7703 BRD-K62056274 HCC515 10 uM 6 h 0.25 1.05 0.16 0.0 0.0 0.0
7905 BRD-K62056274 HT29 10 uM 24 h 0.0 0.0 0.0 -0.24 -0.81 0.14
8110 BRD-K62056274 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.36 -1.2 1.16
8527 BRD-K62056274 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
8839 BRD-K62056274 VCAP 10 uM 6 h -0.23 -0.97 0.1 -0.27 -0.91 0.3
99299 BRD-K62056274 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).